GNC / GLC Active Projects

Global NASH Council & Global Liver Council

74 Research Projects — 2025 to Date

SURVEY PROJECTS

NumTitle
8Pediatric MASLD Knowledge Survey
7Africa Sub Committee: survey to determine knowledge and resource needs
6Global Survey of physician knowledge about management of chronic hepatitis C
5Global Survey of Physician Management of HCV related Fibrosis and HCC
4Hepatitis C and Pregnancy provider survey
3Hepatitis B & D provider survey
1Global Survey of Providers Regarding NITs for MASLD
2ALD Stigma Survey: patient and provider surveys

PROSPECTIVE REGISTRIES

NumTitle
10Collaboration with King Faisal Specialist Research Hospital — submitted variety of abstracts mutually. GNC/CORLD helped implement Global Liver Registry at King Faisal and the Ministry of Defense using REDCap within hospital systems
9Global Liver Registry: Prospective enrollment of 5 liver diseases (MASLD/MASH, HCV, HBV, PBC and ALD) across 30 clinical centers around the globe

CME EDUCATIONAL INITIATIVES

NumTitle
13MASH Alliance Program: 10 regional city series across the US
12MASH Alliance City Series: 25 regional city series across the US
11MASH Alliance Program: In partnership with CLDF, GHAAP and the GNC; provided educational content to over 300 CME programs across the United States

GUIDELINE / CONSENSUS PAPERS

NumTitle
16Focused Recommendations for Management of MASLD by APPs in the U.S.
15Updated Global Consensus Recommendations for Risk Stratification, Treatment Initiation, and Response Monitoring in Metabolic Dysfunction-Associated Steatotic Liver Disease
14Global Consensus Recommendation for MASLD

LARGE RETROSPECTIVE STUDIES

NumTitle
26G-MASLD: Post-Transplant for MASLD/MASH: A Global Study
25G-MASLD: MASLD and Viral Hepatitis and HIV Project
24G-MASLD HCC in MASLD Project
23G-MASLD Central Pathology Readout and Morphometry Project
22G-MASLD Burden of MetALD Project
21G-MASLD Lean MASLD Subproject
20Ballooning of Hepatocytes and Long-Term Outcomes in MASLD Subproject
19G-MASLD Outcomes Subproject
18G-MASLD NIT Performance Subproject
17Global-MASLD (G-MASLD) Project: liver biopsy data analysis

BIOMARKER PROJECTS

NumTitle
28Pruritus and Bile Acid in MASLD Project
27PEth Testing in a Cohort of MASLD: Biomarker Project

HRQL AND PRO PROJECTS

NumTitle
32MASH-CLDQ Validation Project
31Impairment of Cognition, Concentration and Memory in MASLD: The Impact on HRQL
30Viral Hepatitis and Superimposed MASLD: Impact on PROs; VH, Fatigue and Work Productivity
29CLDQ-ALD Development & Validation Study

ECONOMIC ANALYSIS & META-ANALYSIS PROJECTS

NumTitle
38Cirrhosis in MASLD Meta-Analysis
37MASLD-Related HCC Meta-Analysis
36Economic and Clinical Burden of MASH Among Those with Obesity (US, Germany, Spain, Brazil, Saudi Arabia, Japan, France, Italy & UK)
35Economic and Clinical Burden of MASH Among Patients with T2D in 9 Countries
34Economic Burden of MASH in 9 Countries (US, UK, Saudi Arabia, Japan, Germany, Italy, France, Spain, and Brazil)
33Cost Effectiveness of Screening for High-Risk MASLD (United States and United Kingdom)

TRANSPLANTATION

NumTitle
43Transplants for ALD: Liver Transplantation for Alcoholic Hepatitis vs. Cirrhosis — U.S. Registry Data
42UNOS & ELITA Liver Transplantation Databases: Transplants for Hepatic Tumors (Malignant and Benign)
41UNOS & ELITA Liver Transplantation Databases: Transplantation for PBC and PSC
40UNOS & ELITA Liver Transplantation Databases: Hepatitis Delta and Liver Transplantation
39UNOS & ELITA Liver Transplantation Databases: Overall Outcomes Analysis

EPIDEMIOLOGY AND POLICY PROJECTS RELATED TO SLD

NumTitle
48Evolving Spectrum of Steatotic Liver Disease in the United States Over 35 Years: Impact of Binge Drinking and Metabolic Dysfunction
47Global Nutrition Project: Validation of a Short UPF Questionnaire; Prospective Cohort on CMRFs & MASLD
46Self-Care Avoidance and Stigma in NAFLD/MASLD Focusing on Gender Differences
45Consensus Recommendation for MASLD: Risk Stratification and Treatment
44Managing MASLD through Preventive Hepatology: Integrating Policy Reform, Public Health, and Personalized Care
49Global Structural Pathways Linking Food Affordability, Retail Environments, and Metabolic Risk to MASLD Burden: A Cross-National Ecological Analysis of 156 Countries
50Global Pathways Linking Alcohol Exposure, Food Systems, and Alcohol-Associated Liver Disease
51Clinical Obesity Project: Reconceptualizing Obesity as a Multisystem Clinical Condition — Evidence from NHANES
52Exercise, Activity and MASLD Outcomes: NHANES Project
53Low Disease Awareness Among Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and MASLD Cirrhosis in the United States
54MASLD in Elderly Population (Global Liver Registry Analysis)
55United States APP-Focused Recommendations for MASLD
56MASH Educational Alliance in the United States
57MASLD Educational Material for Patients and Providers in the US (Adults and Pediatrics)
58Trends & Disparities in Steatotic Liver Disease (NHANES 2019–2023) - United States
59Long-Term Outcomes of MetALD & ALD in Youth (NHANES Restricted Data)
60Causes of Premature Mortality Across the Spectrum of SLD in the USA (NVSS)
61Socioeconomic & Environmental Determinants of Preventable MASLD Mortality in the US
62Middle East Burden of MASLD & MASH
63Weekend Warrior Physical Activity Pattern Protects Against MASLD and Mortality Comparable to Regular Weekly Exercise: Findings from a US National Cohort
64Development and Validation of Short Food Frequency Questionnaire
65Omics of MASLD: Analyzing Genomics, Proteomics, and Other Omics Data for 400–500 Patients from the US
66Global Trends and Disparities in Preventable Premature Liver Deaths Due to MASLD: A 20-Year Study in 204 Countries
67Central Obesity Is a Key Determinant of Advanced Fibrosis Across the Spectrum of Steatotic Liver Disease (SLD): A Population-Based Analysis
68Geographic Inequities and Care Pathway Optimization in Primary Biliary Cholangitis (PBC) in the United States
69Healthcare Delivery and Rural–Urban Variation in MASLD-Related Liver Mortality Among Older Adults: A Spatial and Target Trial Analysis
70MASLD Primary Care Roadmap: A Web-Based Clinical Decision Support Tool for Risk Stratification and Management
71The Dynamic Spectrum of Disease of SLD - Nature Gastroenterology & Hepatology 2026
722026 Issue of Clinics in Liver Disease: MASLD and MASH: Clinical Spectrum and Modern Management
73SNPs in MASLD: Comparison of Registry Patients from US and Taiwan
74Lifespan approaches for the prevention and management of SLD - Nature Gastroenterology & Hepatology 2026